Our team of scientists, researchers, clinicians and staff work tirelessly to achieve extraordinary scientific progress in our quest to find a cure for paralysis.
Clinical research involves people who voluntarily give informed consent to serve as research participants without whom the research simply could not be done.
The Miami Project to Cure Paralysis was founded in 1985 with the help of Barth A. Green, M.D. and NFL Hall of Fame linebacker Nick Buoniconti after Nick’s son, Marc, sustained a spinal cord injury during a college football game. The Miami Project is a Center of Excellence at the University of Miami Miller School of Medicine. It is considered the premier investigative research program conducting cutting edge discovery, translational, and clinical investigations targeting spinal cord and brain injuries. Since its inception, research at The Miami Project has changed the landscape of knowledge and therapeutic strategies for spinal cord and traumatic brain injury.
Miami Project Researchers Discover Progressive Motor Circuit Recovery after Cell Transplantation
Manuscript Demonstrates that a Home-Based Respiratory Muscle Training Program Can be Beneficial to Strengthen the Respiratory System to Help Combat COVID-19 and Other Breathing Complications Following SCI
A Miami Project to Cure Paralysis research team recently published a paper that demonstrates positive motor circuit recovery following cell transplantation. The subjects in this study were all sub-acutely spinal cord injured, which means they are within a few weeks of their injury, and determined by post injury testing to be ASIA complete paraplegic.
The Miami Project team previously reported a Phase 1 study in which they transplanted cells from their own body, autologous purified Schwann cells, into the injured area of the spinal cord of participants with complete sub-acute thoracic spinal cord injury (SCI). That study observed no clinical improvements. This manuscript chronicles the longitudinal electrophysiological assessments of that trial. Six participants underwent neurophysiology screening pre-transplantation and had three subsequent post-transplantation assessments, including motor evoked potentials (MEPs), somatosensory evoked potentials (SSEPs), voluntarily triggered electromyography (EMG) and galvanic skin response (GSR). These tests measure motor, sensory and autonomic function and allow scientists to determine if a connection is present. Read the entire story here.
(December 2020) Miami Project / University of Miami Miller School of Medicine researchers, as part of a collaboration with a UM-based biotechnology spin off, Truvitech LLC, and scientists from University of California, San Diego, University of California, Davis, University of … Continued
(December 2020) Ever wanted to learn more about the neurotrauma research underway at The Miami Project? Now is your chance because The Miami Project is offering a Remote Exposure to Neurotrauma Research Program. This is a fully remote, “do at … Continued
The Institute for Neural Engineering at the University of Miami hosted more than 200 neuroscientists and biomedical engineers from leading institutions across the State of Florida during the virtually-held 4th Neural Engineering Research Symposium on October 26th and 27th of … Continued
(November 2020) – A Miami Project to Cure Paralysis research team, led by James Guest, M.D., Ph.D., Clinical Professor, Department of Neurological Surgery and The Miami Project, recently published a paper in Frontiers in Neurology, titled Progressive motor circuit recovery … Continued
(October, 2020) – While the 35th Annual Great Sports Legends Dinner benefiting The Buoniconti Fund to Cure Paralysis had to be held virtually rather than at its traditional standing-room-only New York City hotel ballroom setting, the stories told at the … Continued
I have always wanted to be a physical therapist. My professor told me about The Miami Project, made me love the profession even more because they are an under-served community, their lives changed in an instant. With TMP it was … Continued
I AM: Ricky Palermo. I first fell in love with The Miami Project in 1986, while volunteering as one of the first research participants. I continue to return to participate in studies. I believe their will be a cure for … Continued
I am one of the first people to be implanted with a BMI which allows me to move my paralyzed arm and hand using the power of my thoughts. Researchers at The Miami Project to Cure Paralysis and the Department … Continued