If you would like to be considered for these or future Miami Project trials or studies, please see our Register for a Research Program section, send us a message, or call The Miami Project Education Office at 305-243-7108.


This is open only to people with severe injury to a peripheral nerve (in leg or arm) and is NOT open to people with a spinal cord injury

The Safety and Efficacy of Autologous Human Schwann Cell (ahSC) Augmentation of Nerve Autografts after Severe Peripheral Nerve Injury

Purpose: To evaluate the safety of injecting one’s own Schwann cells along with nerve autograft (eg. sural nerve – the sural nerve is a sensory nerve in the leg) after a severe injury to a major nerve has occurred. The secondary purpose of this research project is to evaluate whether transplanted Schwann cells can enhance recovery of sensory and motor function.

Criteria (Inclusion): 18 – 65 years old; severe sciatic nerve injury; brachial plexus injury; and/or major injury of the arm or leg with nerve loss within the previous year.

Criteria (Exclusion): Unable to safely have an MRI, injury to legs that prevents the study doctor from being able to remove part of the sural nerve if needed; severe nerve injury with a gap length greater than 10 mm; history of radiation or cancer in the area of your nerve injury, which includes primary tumors of the nerve; currently pregnant or test positive for pregnancy upon enrollment; disease that the study doctor believes will interfere with participant’s safety or compliance in relation to the study procedures; history of active substance abuse; allergy to gentamicin; positive for HIV or Hepatitis B or C virus.

Study Start Date: September 24, 2019

Estimated Completion Date: September 1, 2029

Status: Enrolling

Principal Investigators: Allan D. Levi, M.D., Ph.D.    305-243-4781


If you would like to be considered for these or future Miami Project trials or studies, please register now!