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What is Autologous Cell Transplantation?

Autologous cell transplantation refers to cells that come from your own body which are then transplanted into a different area of your own body. This is important because it greatly reduces the risk of your body rejecting the transplanted cells. Schwann cells are excellent candidates for transplantation into humans with SCI because large numbers of human Schwann cells can be prepared for autologous implantation after a simple surgery for peripheral nerve harvesting (biopsy), and expansion and purification in culture. Autologous SC transplantation offers important safety advantages that include no need for immune suppression, minimal risk of disease transfer, and a low risk of tumor formation.

SCHWANN CELLS

FACULTY STUDYING SCHWANN CELLS

Mary Bartlett Bunge, Ph.D.
Schwann Cells insulating axons

James D. Guest, M.D., Ph.D.
Schwann Cells in culture

Allan D. Levi, M.D., Ph.D.
Schwann Cells in peripheral nerve.

Paula V. Monje, Ph.D.
Immature Schwann Cell and Differentiated Schwann Cells

Damien D. Pearse, Ph.D.
Schwann Cells associating with axons

Patrick M. Wood, Ph.D.
Human Schwann Cells