| | Home > Our Research Faculty > James D. Guest, M.D., Ph.D.
JAMES D. GUEST, M.D.,PH.D.Associate Professor, Neurological Surgery Cellular and Molecular Strategies to Achieve Long Tract Regeneration in the Spinal Cord Research Interests | 
The current focus of the Guest lab is on the transplantation of autologous glial cells to repair spinal cord injuries. We utilize several types of animal models with an emphasis on solving translational questions related to human clinical application. We also emphasize minimally-invasive surgical lesion-making and transplantation techniques. Sophisticated outcome assessment techniques are used to evaluate transplant effects in both the acute and chronic state of injury. These include kinematic assessment of hand function and gait, electrophysiologic study of conduction across lesion sites, and sensory testing. Other areas of research include studies of human post-mortem spinal cord tissue, intraoperative human spinal cord conduction studies, and research design for human clinical trials. |
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